Thursday, March 24, 2011

Leukemia Cells May Hide in Fat Tissue

(HealthDay News) -- Leukemia cells can hide in fat tissue to evade chemotherapy, which may explain why obese children with leukemia are more likely to develop chemotherapy resistance and have higher relapse rates, researchers say.

A previous study found that obese children with leukemia are 50 percent more likely to relapse than lean children.

In this new study, researchers observed that obese mice with leukemia had higher relapse rates than lean mice after they were treated with the first-line chemotherapy drug vincristine. In the mice that relapsed, leukemia cells were found to be hiding in fat tissue during chemotherapy. Read more...

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