Showing posts with label How the Liver Detoxifies Harmful Substances?. Show all posts
Showing posts with label How the Liver Detoxifies Harmful Substances?. Show all posts

Monday, November 23, 2009

How the Liver Detoxifies Harmful Substances?

Basically there are TWO major detoxification pathways inside the liver cells, which are called the Phase 1 and Phase 2 detoxification pathways.

Phase One - Detoxification Pathway
An example of the phase one pathway is the Cytochrome P-450 mixed function oxidase enzyme pathway. These enzymes reside on the membrane system of the liver cells (called Hepatocytes).

Human liver cells possess the genetic code for many isoenzymes of P-450 whose synthesis can be induced upon exposure to specific chemicals. This provides a mechanism of protection from a wide variety of toxic chemicals. Read more...

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